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A dose-dependent system may very well be responsible for this result, with lipophilicity as the governing issue. Inside of a provided established, the existence of the cyclohexyl or an n-butyl group normally amplified antifungal activity, with respect to both equally growth inhibition and cell de-pigmentation on the mycelium, suggesting that the next lipophilicity may strengthen transportation Within the cells. SEM and TEM of M. grisea hyphae confirmed that remedy with probably the most Lively substance (2h) triggered sizeable ultrastructural effects, significantly within the endomembrane process, suggesting a system of motion comparable to that of most azole fungicides. Dissimilarities had been also observed, without any alterations with the cell wall apparent. In conclusion, various compounds confirmed larger inhibition than tricyclazole, and as a consequence present helpful new chemistry for control of M. grisea infections.

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Verlasst euch auf unsere sorgfältig kuratierte Auswahl, um euren Umzug stressfrei und reibungslos zu gestalten.

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